NGS-Panel Dx

GennameReferenzsequenzOMIMRegion
AKT1NM_005163.2164730Exon 3
APCNM_000038.5611731gesamte kodierende Sequenz
BRAFNM_004333.4164757Exon 15
EGFRNM_005228.3131550Exon 12, 18, 19, 20, 21, fokale Amplifikation
ERBB2NM_004448.2164870Exon 14, 17, 18, 19, 20, 21, 24, 26, fokale Amplifikation
HRASNM_001130442.2190020Exon 2, 3
KRASNM_033360.2190070Exon 2, 3, 4
MAP2K1NM_002755.3176872Exon 1, 2, 3, 6, 7, 8, 9
METNM_001127500.1164860Exon 13, 14, 15, 16, fokale Amplifikation
NRASNM_002524.4164790Exon 2, 3, 4
PIK3CANM_006218.2171834Exon 10, 21
TP53NM_000546.5191170gesamte kodierende Sequenz

 

GennameReferenzsequenzOMIMRegion
AKT1NM_005163.2164730Exon 3
ALKNM_004304.4611731Exon 21, 22, 23, 24, 25, Fusion
BRAFNM_004333.4164757Exon 15
CTNNB1NM_001904.3116806Exon 3
DDR2NM_001014796.1191311gesamte kodierende Sequenz
EGFRNM_005228.3131550Exon 12, 18, 19, 20, 21, fokale Amplifikation
ERBB2NM_004448.2164870Exon 14, 17, 18, 19, 20, 21, 24, 26, fokale Amplifikation
HRASNM_001130442.2190020Exon 2, 3
KITNM_000222.2164920Exon 8, 9, 10, 11, 13, 14, 17, 18
KRASNM_033360.2190070Exon 2, 3, 4
MAP2K1NM_002755.3176872Exon 1, 2, 3, 6, 7, 8, 9
METNM_001127500.1164860Exon 13, 14, 15, 16, fokale Amplifikation
NRASNM_002524.4164790Exon 2, 3, 4
PIK3CANM_006218.2171834Exon 10, 21
RETNM_020975.4164761Fusion
ROS1NM_002944.2165020 Fusion
STK11NM_000455.4602216gesamte kodierende Sequenz
TP53NM_000546.5191170gesamte kodierende Sequenz

 

GennameReferenzsequenzOMIMRegion
BAP1NM_004656.3 603089gesamte kodierende Sequenz
BRAFNM_004333.4164757Exon 15
GNA11NM_002067.2139313Exon 5
GNAQNM_002072.3600998Exon 5
KITNM_000222.2164920Exon 8, 9, 10, 11, 13, 14, 17, 18
MAP2K1NM_002755.3176872Exon 1, 2, 3, 6, 7, 8, 9
METNM_001127500.1164860Exon 13, 14, 15, 16, fokale Amplifikation
NRASNM_002524.4164790Exon 2, 3, 4
PDGFRANM_006206.4173490Exon 12, 14, 18
TP53NM_000546.5191170gesamte kodierende Sequenz

 

GennameReferenzsequenzOMIMRegion
BCORNM_001123385.1 300485gesamte kodierende Sequenz
BRAFNM_004333.4164757Exon 15
CDKN2ANM_001195132.1600160gesamte kodierende Sequenz
CDKN2BNM_004936.3600431gesamte kodierende Sequenz
CDKN2CNM_078626.2603369gesamte kodierende Sequenz
EGFRNM_005228.3131550Exon 12, 18, 19, 20, 21, fokale Amplifikation
H3F3ANM_002107.4 601128Exon 2
IDH1NM_005896.3147700Exon 4
IDH2NM_002168.3147650Exon 4
KITNM_000222.2164920Exon 8, 9, 10, 11, 13, 14, 17, 18
KRASNM_033360.2190070Exon 2, 3, 4
METNM_001127500.1164860Exon 13, 14, 15, 16, fokale Amplifikation
NRASNM_002524.4164790Exon 2, 3, 4
PDGFRANM_006206.4173490Exon 12, 14, 18
PIK3CANM_006218.2171834Exon 10, 21
PTENNM_000314.6601728gesamte kodierende Sequenz
STAG2NM_001042749.2300826gesamte kodierende Sequenz
TERTNM_198253.2187270Promoterregion
TP53NM_000546.5191170gesamte kodierende Sequenz

 

GennameReferenzsequenzOMIMRegion
BRAFNM_004333.4164757Exon 15
EGFRNM_005228.3131550Exon 12, 18, 19, 20, 21, fokale Amplifikation
ERBB2NM_004448.2164870Exon 14, 17, 18, 19, 20, 21, 24, 26, fokale Amplifikation
HRASNM_001130442.2190020Exon 2, 3
KRASNM_033360.2190070Exon 2, 3, 4
METNM_001127500.1164860fokale Amplifikation
NRASNM_002524.4164790Exon 2, 3, 4
PIK3CANM_006218.2171834Exon 10, 21
RETNM_020975.4164761Exon 2, 5, 7, 9, 10, 11, 13, 14, 15, 16, 17, 18, 19, Fusion
TERT NM_198253.2187270Promoterregion
TP53NM_000546.5191170gesamte kodierende Sequenz

 

Die gesamte Genliste ist auf Anfrage erhältlich (nicht akkreditiertes Verfahren)

GennameReferenzsequenzOMIMRegion
ASXL1NM_015338.5 612990Exon 12, 13
CALRNM_004343.3109091Exon 9
CBLNM_005188.3165360Exon 8, 9
CEBPANM_004364116897Exon 1
CSF3RNM_156039.3138971Exon 14, 17
DNMT3ANM_022552.4602769gesamte kodierende Sequenz
EZH2NM_004456.4601573gesamte kodierende Sequenz
FLT3NM_004119.2 136351Exon 14, 15, 20
IDH1NM_005896.3147700Exon 4
IDH2NM_002168.3147650Exon 4
JAK2NM_004972.3147796Exon 12, 14
JAK3NM_000215.3600173Exon 13
KITNM_000222.2164920Exon 8, 9, 10, 11, 13, 14, 17, 18
KRASNM_033360.2190070Exon 2, 3, 4
MPLNM_005373.2159530Exon 10
NOTCH1NM_017617.4190198Exon 26, 27, 31, 34
NOTCH2NM_024408.3600275Exon 26, 27, 31, 34
NPM1NM_002520.6164040Exon 11
PTPN11NM_002834.4176876Exon 3, 13
RUNX1NM_001754.4 151385gesamte kodierende Sequenz
SETBP1NM_015559.2 611060Exon 4
SF3B1NM_012433.3 605590Exon 13, 14, 15, 16
SRSF2NM_001195427600813Exon 1, 2
TET2NM_001127208.2612839gesamte kodierende Sequenz
TP53NM_000546.5191170gesamte kodierende Sequenz
U2AF1NM_006758.2191317Exon 2, 5, 6

 

GennameReferenzsequenzOMIMRegion
CARD11NM_032415.5 607210Exon 4, 5, 6, 7, 8, 9, 10
CD79BNM_001039933.2, NM_000626.3147245Exon 5, 6 (partiell)
CREBBPNM_004380.2600140gesamte kodierende Sequenz
EZH2NM_004456.4601573Exon 16, 18
GNA13NM_006572.5604406gesamte kodierende Sequenz
MYD88NM_001172567.1, NM_002468.4
602170Exon 3, 4, 5 (partiell)
PIM1NM_001243186.1, NM_002648.3
164960gesamte kodierende Sequenz
PRDM1NM_001198.3603423gesamte kodierende Sequenz
SOCS1NM_003745.1 603597Exon 2 (partiell)
STAT6NM_001178078.1601512Exon 12, 13, 14
TNFAIP3NM_001270508.1191163gesamte kodierende Sequenz
TNFRSF14NM_003820.3 602746gesamte kodierende Sequenz

 

GennameReferenzsequenzOMIMRegion
ATMNM_000051.3 607585gesamte kodierende Sequenz
BCORNM_001123385.1300485Exon 4, 8
BIRC3NM_001165.4601721gesamte kodierende Sequenz
BTKNM_000061.2300300 Exon 15
EGR2NM_000399.3129010Exon 2, 3
FBXW7NM_033632.3 606278gesamte kodierende Sequenz
KRASNM_033360.2190070Exon 2, 3
MYD88NM_001172567.1602170Exon 3, 4, 5
NOTCH1NM_017617.4190198Exon 26, 27, 28, 34
NRASNM_002524.4164790Exon 2, 3, 4
PLCG2NM_002661.3600220Exon 19, 20, 24
POT1NM_015450.2606478Exon 5 - 19
SAMHD1NM_015474.3606754gesamte kodierende Sequenz
SF3B1NM_012433.3605590Exon 13, 14, 15, 16, 18
TP53NM_000546.5191170gesamte kodierende Sequenz
XPO1NM_003400.3 602559Exon 14, 15, 16

 

GennameReferenzsequenzOMIMRegion
BRCA1NM_007294.3113705gesamte kodierende Region
BRCA2NM_000059.3600185gesamte kodierende Region